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Activation of lymphocytes by brominated nucleoside and cyclic nucleotide analogues: implications for the "second messenger" function of cyclic GMP.
The purine nucleoside guanosine, when derivatized at the C-8 position to give 8-bromoguanosine (8-BrGuo), acquires the capacity to stimulate high-level lymphocyte proliferation in the presence or absence of serum. Direct comparisons were undertaken to determine whether this activity is exerted only...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1981
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349317/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6278483/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.12.7604 |
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