Á lódáil...

Poly(L-lysine) has different membrane transport and drug-carrier properties when complexed with heparin.

Methotrexate (MTX) conjugated to a Mr 3000 poly(L-Lys) markedly inhibits the growth of Pro-3 MtxRII5-3 Chinese hamster ovarian cells, a mutant line known to be drug resistant because of defective MTX transport. In these cells, membrane transport of [3H]MTX-poly(Lys) is sharply decreased by addition...

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Sonraí Bibleagrafaíochta
Main Authors: Shen, W C, Ryser, H J
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1981
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC349314/
https://ncbi.nlm.nih.gov/pubmed/6950400
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