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Identifying aberrant pathways through integrated analysis of knowledge in pharmacogenomics

Motivation: Many complex diseases are the result of abnormal pathway functions instead of single abnormalities. Disease diagnosis and intervention strategies must target these pathways while minimizing the interference with normal physiological processes. Large-scale identification of disease pathwa...

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Detalhes bibliográficos
Main Authors: Hoehndorf, Robert, Dumontier, Michel, Gkoutos, Georgios V.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493115/
https://ncbi.nlm.nih.gov/pubmed/22711793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts350
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