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Low Doses of Exogenous Interferon-γ Attenuated Airway Inflammation Through Enhancing Fas/FasL-Induced CD4(+) T Cell Apoptosis in a Mouse Asthma Model

To investigate whether low doses of exogenous interferon (IFN)-γ attenuate airway inflammation, and the underlying mechanisms, in asthma. C57BL/6 mice (n=42), after intraperitoneal ovalbumin (OVA) sensitization on day 0 and day 12, were challenged with OVA aerosol for 6 consecutive days. Different d...

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Detalhes bibliográficos
Main Authors: Yao, Yinan, Lu, Shan, Li, Hequan, Lu, Guohua, Zhou, Jianying
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493050/
https://ncbi.nlm.nih.gov/pubmed/22994871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jir.2012.0016
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