Enzymatic reduction of oxidized alpha-1-proteinase inhibitor restores biological activity.

The major serum inhibitor of proteolytic activity, alpha-1-proteinase inhibitor (alpha-1-PI), (or alpha-1-antitrypsin) can be readily inactivated by oxidation [Carp, H. & Janoff, A. (1978) Am. Rev. Resp. Dis. 118, 617-621]. This inactivation appears to be due to the oxidation of a critical methi...

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Bibliografske podrobnosti
Main Authors: Abrams, W R, Weinbaum, G, Weissbach, L, Weissbach, H, Brot, N
Format: Artigo
Jezik:Inglês
Izdano: 1981
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC349292/
https://ncbi.nlm.nih.gov/pubmed/7038679
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