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Activation of Toll-like receptor 3 amplifies mesenchymal stem cell trophic factors and enhances therapeutic potency

Clinical trials of bone marrow mesenchymal stem cell (MSC) therapy have thus far demonstrated moderate and inconsistent benefits, indicating an urgent need to improve therapeutic efficacy. Although administration of sufficient cells is necessary to achieve maximal therapeutic benefits, documented MS...

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Autors principals: Mastri, Michalis, Shah, Zaeem, McLaughlin, Terence, Greene, Christopher J., Baum, Leah, Suzuki, Gen, Lee, Techung
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492833/
https://ncbi.nlm.nih.gov/pubmed/22843797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00191.2012
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