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Pannexin1 contributes to pathophysiological ATP release in lipoapoptosis induced by saturated free fatty acids in liver cells

Hepatocyte lipoapoptosis induced by saturated free fatty acids (FFA) contributes to hepatic inflammation in lipotoxic liver injury, and the cellular mechanisms involved have not been defined. Recent studies have shown that apoptosis in nonhepatic cells stimulates ATP release via activation of pannex...

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Autors principals: Xiao, Feng, Waldrop, Shar L., Khimji, Al-karim, Kilic, Gordan
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492830/
https://ncbi.nlm.nih.gov/pubmed/22972801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00175.2012
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