RIG-I detects infection with live Listeria by sensing secreted bacterial nucleic acids

Immunity against infection with Listeria monocytogenes is not achieved from innate immune stimulation by contact with killed but requires viable Listeria gaining access to the cytosol of infected cells. It has remained ill-defined how such immune sensing of live Listeria occurs. Here, we report that...

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Main Authors: Abdullah, Zeinab, Schlee, Martin, Roth, Susanne, Mraheil, Mobarak Abu, Barchet, Winfried, Böttcher, Jan, Hain, Torsten, Geiger, Sergej, Hayakawa, Yoshihiro, Fritz, Jörg H, Civril, Filiz, Hopfner, Karl-Peter, Kurts, Christian, Ruland, Jürgen, Hartmann, Gunther, Chakraborty, Trinad, Knolle, Percy A
Format: Artigo
Language:Inglês
Published: European Molecular Biology Organization 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492734/
https://ncbi.nlm.nih.gov/pubmed/23064150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.274
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