Multi-Purpose Utility of Circulating Plasma DNA Testing in Patients with Advanced Cancers

Tumor genomic instability and selective treatment pressures result in clonal disease evolution; molecular stratification for molecularly targeted drug administration requires repeated access to tumor DNA. We hypothesized that circulating plasma DNA (cpDNA) in advanced cancer patients is largely deri...

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Main Authors: Perkins, Geraldine, Yap, Timothy A., Pope, Lorna, Cassidy, Amy M., Dukes, Juliet P., Riisnaes, Ruth, Massard, Christophe, Cassier, Philippe A., Miranda, Susana, Clark, Jeremy, Denholm, Katie A., Thway, Khin, Gonzalez De Castro, David, Attard, Gerhardt, Molife, L. Rhoda, Kaye, Stan B., Banerji, Udai, de Bono, Johann S.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492590/
https://ncbi.nlm.nih.gov/pubmed/23144797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047020
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