Pyruvate kinase M2 is a novel diagnostic marker and predicts tumour progression in human biliary tract cancer

BACKGROUND AND AIM: The early diagnosis of biliary tract cancer (BTC) remains challenging and there are few effective therapies. We investigated whether the M2 isotype of pyruvate kinase (M2-PK), which serves as the key regulator of cellular energy metabolism in proliferating cells, could play a rol...

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Detalhes bibliográficos
Main Authors: Dhar, Dipok Kumar, Olde Damink, Steven WM, Brindley, James Hal, Godfrey, Andrew, Chapman, Michael H, Sandanayake, Neomal S, Andreola, Fausto, Mazurek, Sybille, Hasan, Tayyaba, Malago, Massimo, Pereira, Stephen P
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492546/
https://ncbi.nlm.nih.gov/pubmed/22864959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.27611
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