Single dose oral dexamethasone versus multi-dose prednisolone in the treatment of acute exacerbations of asthma in children who attend the emergency department: study protocol for a randomized controlled trial

BACKGROUND: Asthma is a major cause of pediatric morbidity and mortality. In acute exacerbations of asthma, corticosteroids reduce relapses, subsequent hospital admission and the need for ß(2)-agonist therapy. Prednisolone is relatively short-acting with a half-life of 12 to 36 hours, thereby requir...

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Autors principals: Cronin, John, Kennedy, Una, McCoy, Siobhan, an Fhailí, Sinéad Nic, Crispino-O’Connell, Gloria, Hayden, John, Wakai, Abel, Walsh, Sean, O’Sullivan, Ronan
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Study Protocol
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492215/
https://ncbi.nlm.nih.gov/pubmed/22909281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6215-13-141
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