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The Ca(2+) Influence on Calmodulin Unfolding Pathway: A Steered Molecular Dynamics Simulation Study
The force-induced unfolding of calmodulin (CaM) was investigated at atomistic details with steered molecular dynamics. The two isolated CaM domains as well as the full-length CaM were simulated in N-C-terminal pulling scheme, and the isolated N-lobe of CaM was studied specially in two other pulling...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3492193/ https://ncbi.nlm.nih.gov/pubmed/23145050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049013 |
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