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SAMHD1: a new contributor to HIV-1 restriction in resting CD4(+) T-cells

Resting CD4(+) T-cells are critical for establishing HIV-1 reservoirs. It has been known for over two decades that resting CD4(+) T-cells are refractory to HIV-1 infection, but the underlying mechanisms are not fully understood. Compared with activated CD4(+) T-cells that support HIV-1 infection, re...

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Detalhes bibliográficos
Autor principal: Wu, Li
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492151/
https://ncbi.nlm.nih.gov/pubmed/23092163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-9-88
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