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DlgS97/SAP97, a Neuronal Isoform of Discs Large, Regulates Ethanol Tolerance

From a genetic screen for Drosophila melanogaster mutants with altered ethanol tolerance, we identified intolerant (intol), a novel allele of discs large 1 (dlg1). Dlg1 encodes Discs Large 1, a MAGUK (Membrane Associated Guanylate Kinase) family member that is the highly conserved homolog of mammali...

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Hlavní autoři: Maiya, Rajani, Lee, Seonok, Berger, Karen H., Kong, Eric C., Slawson, Justin B., Griffith, Leslie C., Takamiya, Kogo, Huganir, Richard L., Margolis, Ben, Heberlein, Ulrike
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492131/
https://ncbi.nlm.nih.gov/pubmed/23145041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048967
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