Serotonin receptor-mediated stimulation of bovine smooth muscle cell prostacyclin synthesis and its modulation by platelet-derived growth factor.

Serotonin (5-hydroxytryptamine; 0.5 microM and above) stimulated the synthesis of prostacyclin (as measured by radioimmunoassay of 6-ketoprostaglandin F1 alpha) by bovine aortic smooth muscle cells in culture. This effect was structurally specific; a similar response was not elicited by the other in...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Coughlin, S R, Moskowitz, M A, Antoniades, H N, Levine, L
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1981
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349210/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7031670/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.11.7134
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