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Huntington's Disease and its therapeutic target genes: a global functional profile based on the HD Research Crossroads database

BACKGROUND: Huntington’s disease (HD) is a fatal progressive neurodegenerative disorder caused by the expansion of the polyglutamine repeat region in the huntingtin gene. Although the disease is triggered by the mutation of a single gene, intensive research has linked numerous other genes to its pat...

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Detalles Bibliográficos
Main Authors: Kalathur, Ravi Kiran Reddy, Hernández-Prieto, Miguel A, Futschik, Matthias E
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492045/
https://ncbi.nlm.nih.gov/pubmed/22741533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2377-12-47
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