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Cellular immunity of mice to Leishmania donovani in vitro: lymphokine-mediated killing of intracellular parasites in macrophages.

Leishmania donovani, an intracellular protozoan, causes kala-azar by parasitizing the macrophages of its mammalian host. Outbred NCS and CD-1 mice develop immunity to this parasite. This immunity was demonstrable when supernatant fluids from cultured splenic lymphocytes were added to infected macrop...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Chang, K P, Chiao, J W
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1981
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349199/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6947274/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.11.7083
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