Interleukin-7 Ameliorates Immune Dysfunction and Improves Survival in a 2-Hit Model of Fungal Sepsis

Background. Secondary hospital-acquired fungal infections are common in critically-ill patients and mortality remains high despite antimicrobial therapy. Interleukin-7 (IL-7) is a potent immunotherapeutic agent that improves host immunity and has shown efficacy in bacterial and viral models of infec...

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Autors principals: Unsinger, Jacqueline, Burnham, Carey-Ann D., McDonough, Jacquelyn, Morre, Michel, Prakash, Priya S., Caldwell, Charles C., Dunne, W. Michael, Hotchkiss, Richard S.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
Matèries:
Major Articles and Brief Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491749/
https://ncbi.nlm.nih.gov/pubmed/22693226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jis383
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