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Precise probes of type II interferon activity define the origin of interferon signatures in target tissues in rheumatic diseases

Elucidating the molecular pathways active in pathologic tissues has important implications for defining disease subsets, selecting therapy, and monitoring disease activity. The development of therapeutics directed at IFN-α or IFN-γ makes the discovery of probes that report precisely on the activity...

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Autors principals: Hall, John C., Casciola-Rosen, Livia, Berger, Alan E., Kapsogeorgou, Efstathia K., Cheadle, Chris, Tzioufas, Athanasios G., Baer, Alan N., Rosen, Antony
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491524/
https://ncbi.nlm.nih.gov/pubmed/23045702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209724109
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