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Hemin inhibits ATP-dependent ubiquitin-dependent proteolysis: role of hemin in regulating ubiquitin conjugate degradation.

Hemin has been shown to inhibit specifically the energy-dependent degradation of normal and abnormal proteins in reticulocytes [Etlinger, J. D. & Goldberg, A. L. (1980) J. Biol. Chem. 255, 4563-4568]. The present work demonstrates that the action of hemin involves the multi-enzyme ATP-dependent ubiq...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Haas, A L, Rose, I A
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1981
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349148/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6273891/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.11.6845
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