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Glucocorticoids regulate arrestin gene expression and redirect the signaling profile of G protein-coupled receptors
G protein-coupled receptors (GPCRs) compose the largest family of cell surface receptors and are the most common target of therapeutic drugs. The nonvisual arrestins, β-arrestin-1 and β-arrestin-2, are multifunctional scaffolding proteins that play critical roles in GPCR signaling. On binding of act...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3491462/ https://ncbi.nlm.nih.gov/pubmed/23045642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209411109 |
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