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The Pathological and Physiological Roles of IL-6 Amplifier Activation

The NFκB-triggered positive feedback loop for IL-6 signaling in type 1 collagen+ non-immune cells (IL-6 amplifier) was first discovered to be a synergistic signal that is activated following IL-17A and IL-6 stimulation in type 1 collagen+ non-immune cells. Subsequent disease models have shown that i...

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Detalhes bibliográficos
Main Authors: Murakami, Masaaki, Hirano, Toshio
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491450/
https://ncbi.nlm.nih.gov/pubmed/23136555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.4828
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