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Bridging of IgE receptors activates phospholipid methylation and adenylate cyclase in mast cell plasma membranes.

Bridging of IgE receptors on normal rat mast cells by divalent anti-receptor antibodies induced phospholipid methylation and an increase in intracellular cyclic AMP within 15 sec after the receptor bridging. These biochemical events were followed by Ca2+ influx and histamine release. When IgE recept...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Ishizaka, T, Hirata, F, Sterk, A R, Ishizaka, K, Axelrod, J A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1981
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349141/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6273889/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.11.6812
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