E2F mediates enhanced alternative polyadenylation in proliferation

BACKGROUND: The majority of mammalian genes contain multiple poly(A) sites in their 3' UTRs. Alternative cleavage and polyadenylation are emerging as an important layer of gene regulation as they generate transcript isoforms that differ in their 3' UTRs, thereby modulating genes' resp...

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Bibliografiska uppgifter
Huvudupphovsmän: Elkon, Ran, Drost, Jarno, van Haaften, Gijs, Jenal, Mathias, Schrier, Mariette, Oude Vrielink, Joachim AF, Agami, Reuven
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2012
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491381/
https://ncbi.nlm.nih.gov/pubmed/22747694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2012-13-7-r59
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