E2F mediates enhanced alternative polyadenylation in proliferation

BACKGROUND: The majority of mammalian genes contain multiple poly(A) sites in their 3' UTRs. Alternative cleavage and polyadenylation are emerging as an important layer of gene regulation as they generate transcript isoforms that differ in their 3' UTRs, thereby modulating genes' resp...

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Main Authors: Elkon, Ran, Drost, Jarno, van Haaften, Gijs, Jenal, Mathias, Schrier, Mariette, Oude Vrielink, Joachim AF, Agami, Reuven
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2012
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491381/
https://ncbi.nlm.nih.gov/pubmed/22747694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2012-13-7-r59
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