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Bisphosphonate-induced gastrointestinal mucosal injury is mediated by mitochondrial superoxide production and lipid peroxidation

Bisphosphonates such as alendronate and risedronate are commonly used for the treatment of postmenopausal osteoporosis. They have the gastrointestinal adverse effects such as erosions and ulcers in stomach and small intestine. However, the detailed biological mechanism remains to be elucidated. Sinc...

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Bibliografische gegevens
Hoofdauteurs: Nagano, Yumiko, Matsui, Hirofumi, Shimokawa, Osamu, Hirayama, Aki, Nakamura, Yukio, Tamura, Masato, Rai, Kanho, Kaneko, Tsuyoshi, Hyodo, Ichinosuke
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: the Society for Free Radical Research Japan 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491244/
https://ncbi.nlm.nih.gov/pubmed/23170047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3164/jcbn.12-41
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