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Decreased lactate concentration and glycolytic enzyme expression reflect inhibition of mTOR signal transduction pathway in B-cell lymphoma

Application of the kinase inhibitors in cancer treatment is rapidly growing. However, the methods for monitoring the effectiveness of the inhibitors are still poorly developed and currently rely mainly on tracking changes in the tumor volume, a rather late and relatively insensitive marker of therap...

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Detalhes bibliográficos
Main Authors: Lee, Seung-Cheol, Marzec, Michal, Liu, Xiaobin, Wehrli, Suzanne, Kantekure, Kanchan, Ragunath, Puthiyaveettil N, Nelson, David S., Delikatny, Edward J., Glickson, Jerry D., Wasik, Mariusz A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491096/
https://ncbi.nlm.nih.gov/pubmed/22711601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.2825
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