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Global Multi-Method Analysis of Affinities and Cooperativity in Complex Systems of Macromolecular Interactions
Cooperativity, multi-site and multi-component interactions are hallmarks of biological systems of interacting macromolecules. Their thermodynamic characterization is often very challenging due to the notoriously low information content of binding isotherms. We introduce a strategy for the global mul...
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2012
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3491091/ https://ncbi.nlm.nih.gov/pubmed/23020071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac302357w |
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