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Mannose-Binding Lectin Regulates Host Resistance and Pathology during Experimental Infection with Trypanosoma cruzi

Mannose-binding lectin (MBL) is a humoral pattern-recognition molecule important for host defense. Although recent genetic studies suggest an involvement of MBL/MASP2-associated pathways in Chagas’ disease, it is currently unknown whether MBL plays a role in host resistance to the intracellular prot...

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Autors principals: Rothfuchs, Antonio Gigliotti, Roffê, Ester, Gibson, Amanda, Cheever, Allen W., Ezekowitz, R. Alan B., Takahashi, Kazue, Steindel, Mario, Sher, Alan, Báfica, André
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490958/
https://ncbi.nlm.nih.gov/pubmed/23139754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047835
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