SWOG 0514: A phase II study of sorafenib in patients with unresectable or metastatic gallbladder carcinoma and cholangiocarcinoma

OBJECTIVES: Gallbladder and cholangiocarcinomas represent a heterogeneous group of malignant diseases that commonly present at an advanced stage and that have limited therapeutic options. Based on the role of the Ras-Raf-Mek-Erk pathway and the VEGF axis in biliary carcinomas, we conducted a phase I...

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Detalhes bibliográficos
Main Authors: El-Khoueiry, Anthony B., Rankin, Cathryn J., Ben-Josef, Edgar, Lenz, Heinz-Josef, Gold, Philip J., Hamilton, R. Darryl, Govindarajan, Rangaswamy, Eng, Cathy, Blanke, Charles D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490705/
https://ncbi.nlm.nih.gov/pubmed/21748296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-011-9719-0
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