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Prevention of neonatal hyperbilirubinemia by tin protoporphyrin IX, a potent competitive inhibitor of heme oxidation.

The effects of various metalloporphyrins on hepatic heme oxygenase (EC 1.14.99.3) activity were examined in order to identify compounds that could inhibit heme degradation to bile pigment and might therefore be utilized to suppress the development of hyperbilirubinemia in the newborn. Among nine met...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Drummond, G S, Kappas, A
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1981
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349060/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6947237/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.10.6466
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