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Neo-Islet Formation in Liver of Diabetic Mice by Helper-dependent Adenoviral Vector-Mediated Gene Transfer

Type 1 diabetes is caused by T cell-mediated autoimmune destruction of insulin-producing cells in the pancreas. Until now insulin replacement is still the major therapy, because islet transplantation has been limited by donor availability and by the need for long-term immunosuppression. Induced isle...

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Autors principals: Li, Rongying, Oka, Kazuhiro, Yechoor, Vijay
Format: Artigo
Idioma:Inglês
Publicat: MyJove Corporation 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490299/
https://ncbi.nlm.nih.gov/pubmed/23093064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/4321
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