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Examination of Thymic Positive and Negative Selection by Flow Cytometry

A healthy immune system requires that T cells respond to foreign antigens while remaining tolerant to self-antigens. Random rearrangement of the T cell receptor (TCR) α and β loci generates a T cell repertoire with vast diversity in antigen specificity, both to self and foreign. Selection of the rep...

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Sonraí Bibleagrafaíochta
Main Authors: Hu, Qian, Nicol, Stephanie A., Suen, Alexander Y.W., Baldwin, Troy A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: MyJove Corporation 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490290/
https://ncbi.nlm.nih.gov/pubmed/23093039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/4269
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