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Examination of Thymic Positive and Negative Selection by Flow Cytometry
A healthy immune system requires that T cells respond to foreign antigens while remaining tolerant to self-antigens. Random rearrangement of the T cell receptor (TCR) α and β loci generates a T cell repertoire with vast diversity in antigen specificity, both to self and foreign. Selection of the rep...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
MyJove Corporation
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3490290/ https://ncbi.nlm.nih.gov/pubmed/23093039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/4269 |
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