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High efficiency, Site-specific Transfection of Adherent Cells with siRNA Using Microelectrode Arrays (MEA)

The discovery of RNAi pathway in eukaryotes and the subsequent development of RNAi agents, such as siRNA and shRNA, have achieved a potent method for silencing specific genes(1-8) for functional genomics and therapeutics. A major challenge involved in RNAi based studies is the delivery of RNAi agent...

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Detalhes bibliográficos
Main Authors: Patel, Chetan, Muthuswamy, Jit
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490251/
https://ncbi.nlm.nih.gov/pubmed/23007885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/4415
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