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Effects of echinomycin on endothelin-2 expression and ovulation in immature rats primed with gonadotropins

Echinomycin is a small-molecule inhibitor of hypoxia-inducible factor-1 DNA-binding activity, which plays a crucial role in ovarian ovulation in mammalians. The present study was designed to test the hypothesis that hypoxia-inducible factor (HIF)-1α-mediated endothelin (ET)-2 expressions contributed...

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Detalhes bibliográficos
Main Authors: Wang, Zhengchao, Zhang, Zhenghong, Wu, Yanqing, Chen, Liyun, Luo, Qianping, Zhang, Jisen, Chen, Jiajie, Luo, Zimiao, Huang, Xiaohong, Cheng, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Biochemistry and Molecular Biology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490083/
https://ncbi.nlm.nih.gov/pubmed/22874467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2012.44.10.070
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