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Synthesis of N-phenyl-N-(3-(piperidin-1-yl)propyl)benzofuran-2-carboxamides as new selective ligands for sigma receptors

Novel benzofuran-2-carboxamide ligands, which are selective for sigma receptors, have been synthesized via a microwave-assisted Perkin rearrangement reaction and a modified Finkelstein halogen-exchange used to facilitate N-alkylation. The ligands synthesized are the 3-methyl-N-phenyl-N-(3-(piperidin...

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Detalhes bibliográficos
Main Authors: Marriott, Karla-Sue C., Morrison, Andrew Z., Moore, Misty, Olubajo, Olarongbe, Stewart, Leonard E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490055/
https://ncbi.nlm.nih.gov/pubmed/23084435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2012.09.044
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