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Antiretroviral dynamics determines HIV evolution and predicts therapy outcome

Despite the high inhibition of viral replication achieved by current anti-HIV drugs, many patients fail treatment, often with emergence of drug-resistant virus. Clinical observations show that the relationship between adherence and likelihood of resistance differs dramatically across drug class. We...

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Detalhes bibliográficos
Main Authors: Rosenbloom, Daniel I. S., Hill, Alison L., Rabi, S. Alireza, Siliciano, Robert F., Nowak, Martin A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490032/
https://ncbi.nlm.nih.gov/pubmed/22941277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2892
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