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Expression of early adenovirus genes requires a viral encoded acidic polypeptide.

Host-range mutants of adenovirus 5 that contain a defect in region E1A (0-4.5 units) fail to replicate in HeLa cells and to transform rodent cells. In HeLa cells, these mutants synthesize only the two RNAs from E1A that share the same 5' and 3' termini but differ in length by the amount of internal...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Ricciardi, R P, Jones, R L, Cepko, C L, Sharp, P A, Roberts, B E
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1981
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348989/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6947217/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.10.6121
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