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The Interplay of cis-Regulatory Elements Rules Circadian Rhythms in Mouse Liver
The mammalian circadian clock is driven by cell-autonomous transcriptional feedback loops that involve E-boxes, D-boxes, and ROR-elements. In peripheral organs, circadian rhythms are additionally affected by systemic factors. We show that intrinsic combinatorial gene regulation governs the liver clo...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3489864/ https://ncbi.nlm.nih.gov/pubmed/23144788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046835 |
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