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TAMable tumor-associated macrophages in response to innate RNA sensing

Antitumor effect of PolyI:C (a viral dsRNA analog) has been attributed to dendritic cell (DC)-maturation activity, that drives antitumor NK cells, DC cross-presentation, cytotoxic T lymphocytes and many IFN-inducible genes. According to a recent paper, tumor-infiltrating M2 macrophages are found to...

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Detalhes bibliográficos
Main Authors: Seya, Tsukasa, Shime, Hiroaki, Matsumoto, Misako
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3489733/
https://ncbi.nlm.nih.gov/pubmed/23162785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.19894
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