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Inhibition of Hyaluronan Synthesis Reduces Versican and Fibronectin Levels in Trabecular Meshwork Cells

Hyaluronan (HA) is a major component of the extracellular matrix (ECM) and is synthesized by three HA synthases (HAS). Similarities between the HAS2 knockout mouse and the hdf mutant mouse, which has a mutation in the versican gene, suggest that HA and versican expression may be linked. In this stud...

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Bibliografiske detaljer
Main Authors: Keller, Kate E., Sun, Ying Ying, Vranka, Janice A., Hayashi, Lauren, Acott, Ted S.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3489675/
https://ncbi.nlm.nih.gov/pubmed/23139787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048523
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