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Reducing ligation bias of small RNAs in libraries for next generation sequencing

BACKGROUND: The use of nucleic acid-modifying enzymes has driven the rapid advancement in molecular biology. Understanding their function is important for modifying or improving their activity. However, functional analysis usually relies upon low-throughput experiments. Here we present a method for...

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Detalhes bibliográficos
Main Authors: Sorefan, Karim, Pais, Helio, Hall, Adam E, Kozomara, Ana, Griffiths-Jones, Sam, Moulton, Vincent, Dalmay, Tamas
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3489589/
https://ncbi.nlm.nih.gov/pubmed/22647250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1758-907X-3-4
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