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Reducing ligation bias of small RNAs in libraries for next generation sequencing
BACKGROUND: The use of nucleic acid-modifying enzymes has driven the rapid advancement in molecular biology. Understanding their function is important for modifying or improving their activity. However, functional analysis usually relies upon low-throughput experiments. Here we present a method for...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3489589/ https://ncbi.nlm.nih.gov/pubmed/22647250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1758-907X-3-4 |
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