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Transcriptional response of BALB/c mouse thyroids following in vivo astatine-211 exposure reveals distinct gene expression profiles
BACKGROUND: Astatine-211 ((211)At) is an alpha particle emitting halogen with almost optimal linear energy transfer for creating DNA double-strand breaks and is thus proposed for radionuclide therapy when bound to tumor-seeking agents. Unbound (211)At accumulates in the thyroid gland, and the concep...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3489558/ https://ncbi.nlm.nih.gov/pubmed/22697397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2191-219X-2-32 |
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