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A Prion-mediated Mechanism for Memory Proposed in Drosophila

Memories are remarkably persistent, but rely on transient signaling. The prion-like properties of CPEB suggested a solution to this problem. The paper by Krüttner et al demonstrates that the prion-like domain of Drosophila CPEB functions independently of its RNA binding domain for memory.

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Bibliografiske detaljer
Main Authors: Li, Wanhe, Dubnau, Josh
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488862/
https://ncbi.nlm.nih.gov/pubmed/23083729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2012.10.001
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