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Extraordinarily high evolutionary rate of pseudogenes: evidence for the presence of selective pressure against changes between synonymous codons.

Comparisons of nucleotide sequences of several pseudogenes described to date, including alpha- and beta-globin and immunoglobulin kappa-type variable domain pseudogenes, with those of functional counterparts revealed that pseudogenes accumulate mutations at an extremely high rate uniformly over thei...

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Detalles Bibliográficos
Main Authors: Miyata, T, Hayashida, H
Formato: Artigo
Idioma:Inglês
Publicado: 1981
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC348847/
https://ncbi.nlm.nih.gov/pubmed/6795634
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