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Uptake of extracellular double-stranded RNA by SID-2

Ingested dsRNAs trigger RNA interference (RNAi) in many invertebrates including the nematode Caenorhabditis elegans. Here we show that the C. elegans apical intestinal membrane protein SID-2 is required in C. elegans for the import of ingested dsRNA and, when expressed in Drosophila S2 cells, SID-2...

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Bibliografski detalji
Glavni autori: McEwan, Deborah L, Weisman, Alexandra S, Hunter, Craig P
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488460/
https://ncbi.nlm.nih.gov/pubmed/22902558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.07.014
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