Dioxaphosphorinane-Constrained Nucleic Acid Dinucleotides as Tools for Structural Tuning of Nucleic Acids

We describe a rational approach devoted to modulate the sugar-phosphate backbone geometry of nucleic acids. Constraints were generated by connecting one oxygen of the phosphate group to a carbon of the sugar moiety. The so-called dioxaphosphorinane rings were introduced at key positions along the su...

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Detalhes bibliográficos
Main Authors: Catana, Dan-Andrei, Renard, Brice-Loïc, Maturano, Marie, Payrastre, Corinne, Tarrat, Nathalie, Escudier, Jean-Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
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Review Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488415/
https://ncbi.nlm.nih.gov/pubmed/23150809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/215876
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