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Insulin is essential for accumulation of casein mRNA in mouse mammary epithelial cells.

In the presence of cortisol and prolactin, insulin at concentrations as low as 1 ng/ml significantly stimulates casein synthesis in mammary explants from midpregnant mice; maximal synthesis occurs at 10 ng/ml. However, in the absence of insulin, no detectable immunoprecipitable casein is produced. I...

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Bibliographic Details
Main Authors: Bolander, F F, Nicholas, K R, Van Wyk, J J, Topper, Y J
Format: Artigo
Language:Inglês
Published: 1981
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC348827/
https://ncbi.nlm.nih.gov/pubmed/7029543
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