X-ray structure of the fourth type of archaeal tRNA splicing endonuclease: insights into the evolution of a novel three-unit composition and a unique loop involved in broad substrate specificity

Cleavage of introns from precursor transfer RNAs (tRNAs) by tRNA splicing endonuclease (EndA) is essential for tRNA maturation in Archaea and Eukarya. In the past, archaeal EndAs were classified into three types (α′(2), α(4 )and α(2)β(2)) according to subunit composition. Recently, we have identifie...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Hirata, Akira, Fujishima, Kosuke, Yamagami, Ryota, Kawamura, Takuya, Banfield, Jillian F., Kanai, Akio, Hori, Hiroyuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
Schlagworte:
Structural Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488258/
https://ncbi.nlm.nih.gov/pubmed/22941657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks826
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge