Promoters active in interphase are bookmarked during mitosis by ubiquitination

We analyzed modification of chromatin by ubiquitination in human cells and whether this mark changes through the cell cycle. HeLa cells were synchronized at different stages and regions of the genome with ubiquitinated chromatin were identified by affinity purification coupled with next-generation s...

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Библиографические подробности
Главные авторы: Arora, Mansi, Zhang, Jie, Heine, George F., Ozer, Gulcin, Liu, Hui-wen, Huang, Kun, Parvin, Jeffrey D.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2012
Предметы:
Gene Regulation, Chromatin and Epigenetics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488253/
https://ncbi.nlm.nih.gov/pubmed/22941662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks820
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